Background
The MOI-A study is looking at repurposing losartan, a drug used for high blood pressure, for older adolescents and adults with OI. The study is funded by the EU as part of the REMEDi4ALL Consortium and is running in the UK and Italy. The primary aim of the study is to see if losartan slows down bone turnover. If the study is successful in showing this, then a larger study to determine whether losartan reduces fracture rates will be undertaken.
There has already had patient input to the study design and patient information sheets from BBS members already.
To find out more about this Study and which sites are recruiting please see their website